Natural products


The unique combination of expertise in biology and chemistry, together with extensive expertise in technology development make Acies Bio ideally suited for R&D related to microbial natural products. With our scientific origins in the biosynthesis of polyketides and non-ribosomal peptides, such as tacrolimus, rapamycin and erythromycin, we are capable of rapidly setting up and achieving progress towards improved yield, reduced ratio of impurities or biosynthesis of “unnatural” analogues by biosynthetic engineering. In addition to deep understanding of natural product biosynthesis, we also excel in development of highly efficient isolation and purification procedures and semi-synthetic conversion of natural products to final active ingredients. From pharmaceutically relevant APIs to vitamins and food colorants, Acies Bio is a world-leading institution for strain and fermentation development in the natural products segment.


Work with us